Simulated actin reorganization mediated by motor proteins
Fig 5
Actin and myosin organization is consistent across simulations for varying myosin step sizes.
(A1) The radius of gyration decreases as motor step size is increased, reflecting the formation of actin clusters (Fig 4A). (A2) The area of the polygon enclosing the motor proteins also decreases as motor step size increases, due to motor proteins binding to clustered actin filaments. The parameter values used are khead,bind = 0.2/s, Fs = 100 pN, rangeheads = 15–30 (see Table 1). Solid lines indicate the average and shaded areas indicate the standard deviation over 10 stochastic runs. See Fig 3 for additional measure details.