Conventional measures of intrinsic excitability are poor estimators of neuronal activity under realistic synaptic inputs
Fig 5
Removal of two K-currents from the model neurons produce differential effects on their firing output.
(A) First spike latency vs. input resistance plot for the delayed firing type neurons. Non-filled symbols represent the data after the removal of the Kir-current. (B) Scatter plot of cumulative spike counts from the same set of model neurons (synaptic vs. current step responses). (C) Pooled cumulative spike counts shift in a differential manner when static vs. dynamic inputs are used. D-F: Same plots demonstrating the effects of D-current removal from the stuttering type model neurons.