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Transcriptional bursts explain autosomal random monoallelic expression and affect allelic imbalance

Fig 4

Allelic bias is affected by relative changes in both burst frequency and size.

(A) Comparison between the probability of observing allelic imbalance between the alleles and the actual fraction of cells with the imbalance (n = 7,606 autosomal genes). (B) The relative allelic differences in burst kinetics for each gene, colored by their allelic bias (n = 7,606 genes).

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008772.g004