PEtab—Interoperable specification of parameter estimation problems in systems biology
Fig 1
Specifying parameter estimation problems in PEtab.
(A) Example of a typical setup for data-based modeling. Usually, a model of a biological system is developed and calibrated based on measurements from perturbation experiments, which are linked to the biological model by an observation model. Different instances of a generic model are used to account for different perturbations or measurement setups. (B) Simplified illustration of how different entities from (A) map to different PEtab files (not all table columns are shown).