Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape
Fig 6
The probability that a cell, in the mathematical model, exposed to a radiotherapy dose of 2 Gy survives.
The survival probability S(x, t) is function of a cell’s current cell-cycle phase and oxygenation value, as well as the applied radiotherapy dose. Cells are the most likely to survive radiotherapy when hypoxic.