An electrodiffusive, ion conserving Pinsky-Rinzel model with homeostatic mechanisms
Fig 5
Short term dynamics of the PR and edPR models.
The original PR model (top row) and the edPR model (bottom row) exhibit the same spike shape characteristics. (A) Spike shape in PR model for weak coupling (low coupling conductance) between the soma and the dendrite. (B) Spike shape in PR model for strong coupling (high intracellular conductivity) between the soma and the dendrite. (C) Spike shape in edPR model for weak coupling between the soma and the dendrite. (D) Spike shape in edPR model for strong coupling between the soma and the dendrite. (A-D) A step-stimulus current was turned on at t = 10 s, with stimulus strength being 1.35 μA/cm2 in (A), 0.78 μA/cm2 in (B), 31 pA in (C), and 27 pA in (D). The panels show snapshots of a selected spike. See the Parameterizations section in Methods for a full description of the parameters used.