Activation of the DNA-repair mechanism through NBS1 and MRE11 diffusion
Fig 4
Accumulated fraction of NBS1 in the nucleus.
A: The lines represent the faction of accumulated NBS1 proteins in the nucleus, N(tN) defined by Eq (21). The squares represent the corresponding numerical results for the different starting points. In the short time limit, the two methods agree, which is further highlighted in the insert B. C: The lines represent the faction of accumulated NBS1 proteins in the nucleus for the slow diffusion, N(tN) defined by Eq (19). The squares represent the corresponding numerical results for the different starting points. In the long time limit, the two methods agree, as evidenced in the insert D.