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Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics

Fig 3

Cα RMSF plots for each PAS domain in the dimer.

Structured regions with higher fluctuations are highlighted in green and discussed in text. The long and highly flexible PAS-A loops were excluded from calculation and are indicated by dash lines. Helices and β-strands are represented as black and grey bars, respectively, and labelled according to Fig 1A.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1006021.g003