A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data
Fig 1
Redundant pathway versus non-redundant pathway.
The expressed proteins of the pathway B are a subset of the expressed proteins of the pathway A. There is no evidence that pathway B is regulated since the significance may come from the merit of pathway A. On the contrary, some expressed proteins are unique to pathway A to support that pathway A may be regulated as a pathway group.