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Protein charge distribution in proteomes and its impact on translation

Fig 4

N-terminal positive charge concentration of proteins from different subcellular locations.

Heat map for H. sapiens, D. melanogaster, C. elegans, A. thaliana and S. cerevisiae proteomes showing the average net charge distribution (net charges from amino acids 1 to 30 until 100 to 129) divided into 17 different subcellular locations. Red tiles represent segments with a net positive charge, black tiles represent neutral segments and green tiles represent segments with a net negative charge. N-terminal positive charge concentration is conserved among most subcellular locations, except for endosomes, lysosomes, vacuoles and nucleoplasm proteins.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1005549.g004