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A Mathematical Model of Neonatal Rat Atrial Monolayers with Constitutively Active Acetylcholine-Mediated K+ Current

Fig 5

Steady-state characteristics and time constants of the transient outward K+ current (Ito) generated using the model.

A, steady-state activation (r) and fast and slow inactivation (s, sslow∞) curves. B, activation time constant of the model. C, inactivation time constants (τ) from model. D, normalized peak I-V curve for (Ito), overlaid on patch-clamp data (open circles) derived from Ramos-Mondragόn et al. [35]

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1004946.g005