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Sources of Variability in a Synthetic Gene Oscillator

Fig 13

Implementation of parameter variability.

A rate parameter p changing at cell division due to partitioning effects. While the cell is not dividing, p has the constant value p0 and the reaction rate is R(y, p0), where y is the state of the system. At cell division, the parameter p is different for each cell: p1 for cell 1, and p2 for cell 2. Cells 1 and 2 then have reaction rates R(y, p1) and R(y, p2). The value of p for the daugther cells will remain unchanged until the next division.

Fig 13

doi: https://doi.org/10.1371/journal.pcbi.1004674.g013