An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway
Figure 10
Simulation of CETP inhibition on a virtual population with low HDL-C (≤40 mg/dL).
Each virtual patient selected for the treatment simulation had its rate constants associated with CETP activity and
decreased to 20% of their original values.