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A Combination of Transcriptional and MicroRNA Regulation Improves the Stability of the Relative Concentrations of Target Genes

Figure 2

A. Randomization of miRNA-target links.

Distribution of the number of FFLs for 1000 simulations obtained with JASPAR TFs list and confirmed by at least 4 miRNA databases (Z = 49,4). B. Randomization of miRNA-target links. Distribution of the number of FFLs for 1000 simulations obtained with ENCODE TFs list and confirmed by at least 4 miRNA databases (Z = 23,3). C. Randomization of TF-target links. Distribution of the number of FFLs for 1000 simulations obtained with JASPAR TFs list and confirmed by at least 4 miRNA databases (Z = −20,8). D. Randomization of TF-target links. Distribution of the number of FFLs for 1000 simulations obtained with ENCODE TFs list and confirmed by at least 4 miRNA databases (Z = −18,1).

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003490.g002