Structural Consensus among Antibodies Defines the Antigen Binding Site
Figure 7
Comparison of consensus and method-specific residues.
A light chain is analysed by all methods. In the top comparison, the residues identified by Paratome (grey, top line) are compared to those identified by Kabat (grey, second line). For L1, for example, both methods agree on the fragment ESVDSYGKSFMH, however, according to Kabat, CDR L1 includes also three amino acids N-terminal to this fragment (RAS, marked with a grey box) while according to Paratome these are not included in ABR L1. ABR L2, is identified by Paratome to be longer than the CDR L2 identified by Kabat by four residues (VLIY, marked with a dashed box).