Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes
Figure 3
A network of predicted protein complexes containing 543 proteins and 1,893 interactions.
Complexes are assembled by selecting and visualizing cliques formed by predicted protein-protein interactions ranked in the top 1% by all three methods. The resulting network composed of 63 protein complexes containing 3 to 25 proteins. Yellow nodes are prey and blue nodes are bait proteins. Edges are colored according by the following criteria: White edges are predicted interactions that do not have reported direct or indirect interaction in the literature; Green edges are predicted interactions that have one or more reported indirect interaction; Red edges are recalled direct interactions.