B Cell Activation Triggered by the Formation of the Small Receptor Cluster: A Computational Study
Figure 5
Activation of the cell by the displacement of the nucleus.
The shift of the nucleus by 0.08 causes that locally thickness of the cytoplasm drops to 0.02. This leads to the local cell activation, thereafter the wave of the kinase activity spreads over the rest of the cytoplasm. The concentration of the active kinase is the highest at the pole in which the cytoplasm is the thinnest. The remaining parameters for this simulation are ,
,
.