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Current Estimates for HIV-1 Production Imply Rapid Viral Clearance in Lymphoid Tissues

Figure 1

Viral clearance in the lymphoid tissue, , as a function of the production rate , given by Eq. (14), for a typical patient with cells, , particles, and the indicated clearance rates via the blood, .

In (a) 90% of the virus in lymphoid tissue is associated with FDCs, i.e., , and in (b) this is 50%, i.e., .

doi: https://doi.org/10.1371/journal.pcbi.1000906.g001