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Differential Affinity and Catalytic Activity of CheZ in E. coli Chemotaxis

Figure 5

The effect of the rate of association between CheYp and CheZ bound to the receptor cluster, , on the response of [YpZ] and [Yp] in the differential-affinity-and-catalytic-activity model (Equations 1–3 and Equation 8).

The black line and black symbols corresponds to the CheZ mutant cells (see also Figure 4), while the red line and red symbols correspond to cells containing wild-type CheZ, in which ; the dashed green and blue lines correspond to CheZ-wild-type cells with and , respectively. Please note that as is lowered, the distinction between the two regimes becomes less sharp, because more CheYp molecules diffuse into the cytoplasm before they will bind CheZ molecules. For parameter values, see the caption of Figure 4.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1000378.g005