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Synaptic and dendritic architecture of different types of hippocampal somatostatin interneurons

Fig 7

Electrophysiological properties of OLM and HS cells.

For the explanation of the in vitro experimental workflow, see Fig 1O and 1U. (A, D) Typical voltage responses of OLM and HS cells to depolarizing and hyperpolarizing current steps (amplitude: 160 pA). (B, C) Example voltage responses from an active OLM and an active HS cell model, corresponding to the same stimulation protocol used in the experiments. (E, F) Reconstructions of a biocytin labeled OLM (E) and an HS cell (F). Dendrites are shown in purple and green, whereas axon arbors are shown in black. Cells were pre-labeled for in vitro recordings by Cre-dependent tracer virus injected in the CA1 area of Chrna2-Cre mice (OLM) or Fluospheres injected into the medial septum (HS cells). HS, hippocampo-septal; OLM, oriens-lacunosum-moleculare.

Fig 7

doi: https://doi.org/10.1371/journal.pbio.3002539.g007