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Promote One, Inhibit the Other: A Single Pathway Controls Axon and Dendrite Growth, Oppositely

A functioning neuron (symbolized here as a tree) has both dendritic arbors to receive signals and axonal branches to send them.

The activity of a single molecular pathway (shown as the orange slope) determines whether a neuron grows more dendrites and fewer axons (left tree) or more axons and fewer dendrites (right tree). Image credit: Xin Wang.

doi: https://doi.org/10.1371/journal.pbio.1001575.g001