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Interdigitated Paralemniscal and Lemniscal Pathways in the Mouse Barrel Cortex

Figure 5

Thalamocortical Topographic Transformations

(A) Schematic of the coordinate system. XID and YID are the horizontal and vertical coordinates of the input domain, respectively. XSoma is the horizontal coordinate of the cell position in cortex. XID and XSoma are measured from the VPM/POm boundary (center of the uncaging grid; light red). YID is measured from the bottom of VPM (bottom of the uncaging grid).

(B) and (C) Positions of the input domains (YID in B; XID in C) in VPM (green) and POm (blue) as a function of XSoma. Cells were in L4 (n = 12); L5B (n = 7); L6A (n = 5); and L5A (n = 21). Dashed line shows the linear correlation between XSoma and YID for VPM and POm domains (r2 = 0.72).

Figure 5

doi: https://doi.org/10.1371/journal.pbio.0040382.g005