Abstract
This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.
Conference
Santa María Workshop on Chemistry Devoted to Bioinorganic Chemistry, 2nd, Santa María del Mar, Havana, Cuba, 2003-07-07–2003-07-11
Published Online: 2009-01-01
Published in Print: 2004-01-01
© 2013 Walter de Gruyter GmbH, Berlin/Boston
