We estimate effects of ply thickness in mechanical properties and damage evolution of CFRP angle-ply laminates under various tensile loading. It should be noted that the laminate thickness is almost the same, but the ply thickness are quite different. Monotonic tensile tests, cyclic loading-unloading tensile tests and stress relaxation tensile tests are performed on [(±θ_<12>]_s (t-0.05prepreg× 48plies), [(±θ)_4]_s (t-0.15 prepreg×16plies) and [(+θ)_4/(-θ)_4]_s (t-0.15prepreg×16plies) T700SC/2500 carbon/epoxy laminates with various fiber directions (θ=30, 40, 45, 50 and 67.5°). Ply thickness is expressed as t-0.05, t-0.15 and t-0.6, respectively. Damage evolution can be determined by cyclic loading-unloading tests. We use mesoscale damage model to investigate damage evolution in CFRP laminates. We discuss effect of ply thickness on mechanical property of angle-ply laminates. Laminates have thin ply thickness showed high strength and fracture strain.