On the dental therapy, the orthoprosthesis is manufactured by using the dental CAD//CAM. This can manufacture orthoprosthesis effectively. But, there are some problems that the work materials are hard-to-cut-material and dental technicians have to decide the processing condition. In this study, the process strategy which is high efficiency and keeping long tool life to machine the orthoprosthesis has suggested and demonstrated on the simulation. Therefore, The processes what is used the radius end mill and The contour line process has applied to roughing and semi-finishing and the 5-axis process has applied to finishing. As the result of carried out roughing and semi-finishing, these process staved the cutting by the center of tool edge of ball end mill, the cutting of pushing down and exponential increase of depth of cut. And these process are shorter roughing time than the conventional roughing. But, the semi-finishing is longer than the conventional one.