1999 Volume 52 Issue 11 Pages 711-713
A 6-year-old, male Great Pyrenean dog was hospitalized with a 1-year history of intermittent anorexia, weight loss, polyuria, polydipsia, exercise intolerance, and intermittent mild diarrhea. Hematological examinations revealed anemia, leukocytosis, azotemia, hyperkalemia, and hyponatremia. Endocrine assays indicated a diagnosis of primary hypoadrenocorticism. Treatment with hydrocortisone (1 mg/kg/day) and a quarter of the normal maintenance dose of fludrocortisone acetate (6μg/kg/day) proved effective. The dog was diagnosed as having a synovial sarcoma at the carpal articulation of the left foreleg 172 days after initial presentation. Following surgery and chemotherapy, hypoadrenocorticism remained firmly under control.
