1957 年 77 巻 5 号 p. 544-546
In vitro anthelmintic tests were carried out on naphthocoumarins, its pyrone-ring 4-methyl derivatives, and their reduction products (I to IX), in order to find relationship between chemical structure and anthelmintic effect. Of these, (IVb), (Va and b), and (VIIIa and b) were found to effect revolving motion and curling-up of ascaris, as with santonin, the action especially marked in (IVb).