Studies on Pyrimidine Derivatives. V. Synthesis of Thiazolo [5, 4-d] pyrimidines and Related Compounds. (5).
1958 Volume 6 Issue 4 Pages 349-352
Details
1958 Volume 6 Issue 4 Pages 349-352
4-Mercapto-5-aminopyrimidine (III) was prepared by the following two reactions. 1) The reaction of phosphorus pentasulfide on 4-hydroxy-5-aminopyrimidine. 2) The dehalogenation of 4-mercapto-5-amino-6-chloropyrimidine. Thiazolo [5, 4-d] pyrimidine and 2-methyl-, 2-phenyl-. and 2-mercaptothiazolo [5, 4-d]-pyrimidines were prepared from (III).
