Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Saponins from Chinese Medicinal Plant, Hemsleya graciliflora (Cucurbitaceae)
Ryoji KASAITakahiro TANAKARui-Lin NIEMasazumi MIYAKOSHIJun ZHOUOsamu TANAKA
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1990 Volume 38 Issue 5 Pages 1320-1322

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Abstract

From rhizomes of a Chinese cucurbitaceous medicinal plant, Hemsleya graciliflora, eight oleanolic glucuronide saponins were isolated together with three known cucurbitane-type triterpenes, dihydrocucurbitacin F, 25-O-acetyl-dihydrocucurbitacin F and its 2-O-β-glucosides. Of these saponins, six were known and identified as β-D-glucosyl ester of oleanolic acid, chikusetsusaponins IV a and V and hemslosides Ma1, Ma3 and H1. Structures of two new saponins called hemslosides G1 and G2 were elucidated as β-gentiobiosyl esters of oleanolic acid 3-O-α-L-arabinopyranosyl-(1→3)-β-D-glucuronide and oleanolic acid 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucuronide, respectively.

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© The Pharmaceutical Society of Japan
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