Two new germacranolides, ixerins H and I, and three new melampolides, ixerins J, K and L were isolated from the polar and less polar fractions of Ixeris tamagawaensis KITAM., respectively. The structures and stereochemistry were established partly by chemical transformations and mainly by the use of ¹H-and ¹³C-nuclear magnetic resonance spectroscopy.