Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Diterpene-Glycosides of Stevia Paniculata LAG. : Structures of Aglycones
HIROSHI KOHDAOSAMU TANAKAKOZABURO NISHI
Author information
JOURNAL FREE ACCESS

1976 Volume 24 Issue 5 Pages 1040-1044

Details
Abstract

The leaves of Stevia paniculata (Compositae) which are not sweet unlike the leaves of S. rebaudiana, were shown to contain several glycosides. The enzymatic hydrolysis of the crude glycosides fraction of the leaves gave four aglycones A (II), B (XVI), C (XV) and D (IV). It was proved that II and IV were identical with the known diterpene acids, ent-15α-hydroxykaur-16-en-19-oic acid and ent-16α, 17-dihydroxykauran-19-oic acid, respectively. On the basis of the chemical and physical investigation as well as the comparison of the known kaurene-type diterpenes, XV and XVI could be formulated as ent-11α, 15α-dihydroxykaur-16-en-19-oic acid and its 15-oxo derivative, respectively. From the ether-soluble fraction, taraxasterol and its acetate were also isolated and identified.

Content from these authors
© The Pharmaceutical Society of Japan
Previous article Next article
feedback
Top