Synthesis of 3-Pyridinols. I. Reaction of 5-Unsubstituted Oxazoles with Acrylonitrile

Takeo Naito; Toru Yoshikawa; Fumiyoshi Ishikawa; Sumiro Isoda; Yoshiaki Omura; Isao Takamura

doi:10.1248/cpb.13.869

Takeo Naito, Toru Yoshikawa, Fumiyoshi Ishikawa, Sumiro Isoda, Yoshiaki Omura, Isao Takamura

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JOURNAL FREE ACCESS

1965 Volume 13 Issue 7 Pages 869-872

DOI https://doi.org/10.1248/cpb.13.869

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Abstract

5-Unsubstituted oxazoles were allowed to react with acrylonitrile and structures of the products were determined. 3-Pyridinol derivatives were unexpectedly the main products in these reactions. A possible mechanism forming 3-pyridinols was discussed.

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