3D打印数字化个性化钛网在牙槽嵴引导骨再生中的临床应用

doi:10.12337/zgkqzzxzz.2022.08.003

中国口腔种植学杂志 ›› 2022, Vol. 27 ›› Issue (4): 208-216.DOI: 10.12337/zgkqzzxzz.2022.08.003

3D打印数字化个性化钛网在牙槽嵴引导骨再生中的临床应用

王婷婷¹, 王凤², 吴轶群¹

1 上海交通大学医学院附属第九人民医院口腔第二门诊部上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室中国医学科学院口腔颌面再生医学创新单元 200001;
2 上海交通大学医学院附属第九人民医院口腔种植科上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室中国医学科学院口腔颌面再生医学创新单元 200001

收稿日期:2021-03-21 出版日期:2022-08-30 发布日期:2022-09-07
通讯作者: 吴轶群,Email：yiqunwu@hotmail.com,电话：021-56152705
基金资助:
上海交通大学医学院附属第九人民医院研究型学科基金（KQYJXK2020）; 中国医学科学院医学与健康科技创新工程项目资助（2019-12M-5-037）; 作者简介:吴轶群医学博士,主任医师,博士生导师,上海交通大学医学院附属第九人民医院口腔第二门诊部主任; 现任中华口腔医学会口腔种植专业委员会副主任委员,国际口腔种植协会专家组成员; ITI中国区主席,上海九院爱丁堡皇家外科学院口腔种植与修复培训考试中心主任; 担任“十三五”国家重点研发项目课题负责人,主持国家自然科学基金、上海交通大学医工（理）交叉基金重点项目、国际口腔种植协会（ITI）资助项目等多项国家级、国际级课题项目,研究成果曾获国家科技进步二等奖（2019）、中华口腔医学科技三等奖（2018）、华夏医学奖三等奖（2016）等; 高新科技成果转化1项（2019）,获得国家专利证书12项; 发表论文40余篇,参编著作10部,主译著作1部; 担任《中国口腔种植学杂志》副主编,《口腔疾病防治》《上海口腔医学》《口腔材料器械杂志》编委

Clinical application of three-dimensional printed digital customized titanium mesh in guided bone regeneration for alveolar bone reconstruction

Wang Tingting¹, Wang Feng², Wu Yiqun¹

1 Department of Second Dental Center, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai 200001, China;
2 Department of Oral Implantology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai 200001, China;

Received:2021-03-21 Online:2022-08-30 Published:2022-09-07
Contact: Wu Yiqun, Email: yiqunwu@hotmail.com, Tel: 0086-21-56152705

摘要/Abstract

摘要： 牙槽嵴骨量严重不足极大影响着种植体的植入和种植修复后的长期稳定性,引导骨再生在骨增量方面效果稳定。3D打印数字化个性化钛网是实现理想牙槽嵴骨增量的一种新方法,对骨量不足拟行种植修复的患者,完善术前检查,通过影像学、口内或模型扫描获取牙槽骨及牙列信息,以修复为导向设计种植体植入位置,并规划预期骨增量范围及个性化钛网形状,利用3D打印技术制备个性化钛网。该技术有助于精确、个性化重建骨缺损区的牙槽嵴三维形态。本文拟对患者的术前评估、个性化钛网设计要点、临床应用程序及注意事项进行阐述,以期推动该技术在临床中的广泛安全应用。

关键词: 个性化钛网, 引导骨再生, 3D打印, 骨增量材料, 浓缩生长因子

Abstract: Severe alveolar bone defects seriously affect dental implant placement and its long-term performance. Guided bone regeneration（GBR）as a reliable technique is able to achieve predictable bone augmentation. Three-dimensional printed digital customized titanium mesh is a new technique to obtain alveolar bone augmentation.For patients with severe alveolar bone defects, the preoperative examination is performed, the information of alveolar and dentition is obtained by radiographic examination and oral scan or model scan respectively,then the implants position is placed according to the principle of prosthetic-driven implant placement. The extent of bone augmentation and the shape of customized titanium mesh are designed with software, and then the digital customized titanium mesh is manufactured with 3D printing technology. The application of customized titanium mesh is conducive to reconstruct the three-dimensional shape of alveolar ridge precisely,and individually. The aim of this article is to summarize pre-opreative evaluation of patients, the key points of the design, clinical application and precautions of customized titanium mesh, in order to further promote its wide and safe application in clinical practice.

Key words: Customized titanium mesh, Guided bone augmentation, 3D printing, Bone grafting materials, Concentrated growth factors

王婷婷,等王凤,等吴轶群. 3D打印数字化个性化钛网在牙槽嵴引导骨再生中的临床应用[J]. 中国口腔种植学杂志, 2022, 27(4): 208-216. DOI: 10.12337/zgkqzzxzz.2022.08.003

Wang Tingting, Wang Feng, Wu Yiqun. Clinical application of three-dimensional printed digital customized titanium mesh in guided bone regeneration for alveolar bone reconstruction[J].Chinese Journal of Oral Implantology, 2022, 27(4): 208-216.DOI: 10.12337/zgkqzzxzz.2022.08.003.

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3D打印数字化个性化钛网在牙槽嵴引导骨再生中的临床应用

Clinical application of three-dimensional printed digital customized titanium mesh in guided bone regeneration for alveolar bone reconstruction

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