中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (12): 895-897.doi: 10.12144/zgmfskin202212895

• 病例报告 • 上一篇    下一篇

黏液炎性纤维母细胞性肉瘤一例

徐作佼1,高素美2,王振华1,李惠1,曹哲1,徐陶陶1,孙怡1   

  1. 1潍坊市人民医院皮肤科,山东潍坊,261000;2潍坊市人民医院病理科,山东潍坊,261000
  • 出版日期:2022-12-15 发布日期:2022-10-26

Myxoinflammatory fibroblastic sarcoma: a case report

XU Zuojiao1, GAO Sumei2, WANG Zhenhua1, LI Hui1, CAO Zhe1, XU Taotao1, SUN Yi1   

  1. 1 Department of Dermatology, Weifang People's Hospital, Weifang 261000, China; 2 Department of Pathology, Weifang People's Hospital, Weifang 261000, China
  • Online:2022-12-15 Published:2022-10-26

摘要: 患者,女,69岁。左大腿红色斑块、结节伴瘙痒、疼痛2年。皮肤科查体:多个大小不一红色斑块、结节,质地较硬,基底深在,与周围组织界限不清,融合成片,大小约8.5 cm×11.0 cm,有压痛。组织病理学示:皮下梭形细胞肿瘤,奇异型核多见,局部病理性核分裂像,伴多量淋巴浆细胞浸润,可见间质粘液变性。免疫组化染色:Vimentin (+)、CD68(大部分+)、SMA(+),Ki-67指数(75%)。诊断:黏液炎性纤维母细胞性肉瘤。

关键词: 黏液炎性纤维母细胞性肉瘤, 软组织肿瘤, 罕见病

Abstract: A 69-year-old female presented with red plaques and nodules with pruritus and pain on the left thigh for 2 years. The clinical manifestations were multiple red plaques and nodules of different sizes, with hard texture, deep base, unclear boundary with surrounding tissues, fusion and tenderness, ,and about 8.5 cm×11.0 cm in size. Pathology showed a subcutaneous spindle cell tumor with atypical nuclei, focal pathological mitotic figures, and numerous lymphoplasmacytic infiltrates, with interstitial mucinous degeneration. Immunohistochemical staining: Vimentin(+), CD68 (mostly+)and SMA(+); Ki-67 index (75%). The diagnosis of myxoinflammatory fibroblastic sarcoma was made.

Key words: myxoinflammatory fibroblastic sarcoma, soft tissue neoplasms, rare disease