天然抗氧化剂花青素在饲料添加剂中的应用

doi:10.11923/j.issn.2095-4050.cjas2023-0121

农学学报 ›› 2024, Vol. 14 ›› Issue (5): 60-66.doi: 10.11923/j.issn.2095-4050.cjas2023-0121

天然抗氧化剂花青素在饲料添加剂中的应用

韩姗姗¹(), 岳淑宁², 张红艳², 戴佳锟¹^,², 窦秉德², 李忠玲¹()

¹ 陕西省生物农业研究所，西安 710043
² 陕西省酶工程技术研究中心，陕西临潼 710000

收稿日期:2023-05-15 修回日期:2023-08-11 出版日期:2024-05-20 发布日期:2024-05-16
通讯作者:
李忠玲，女，1973年出生，黑龙江讷河人，硕士，副高级职称，主要从事饲料添加剂与畜禽健康养殖关键技术研究。通信地址：710043 陕西省西安市咸宁中路125号，Tel：029-83825687，E-mail：lizhonglings@126.com。
作者简介:
韩姗姗，女，1983年出生，陕西西安人，中级职称，博士，主要从事功能饲料添加剂的研究。通信地址：710043 陕西省西安市咸宁中路125号，Tel：029-83825687，E-mail：Hanss@xab.ac.cn。
基金资助:
西安市科技局农业技术研发项目“富含玉米花青素替抗饲料的研究与开发”(22NYYF015); 陕西省科学院项目科学研究专项“仔猪无抗饲料产品开发中发酵中药的应用研究”(2021k-11); 陕西省科技厅项目重点研发计划“家禽专用无抗生物饲料添加剂的研究及应用”(2022NY-103); 西安市科技局农业技术研发项目“奶牛粪污无害化处理高效复合生物制剂的研究与应用”(21NYYF0017); 陕西省科学院基础研究面上项目“黑玉米种质资源开发与综合利用技术示范”(2023k-13)

Application of Natural Antioxidant Anthocyanins in Feed Additives

HAN Shanshan¹(), YUE Shuning², ZHANG Hongyan², DAI Jiakun¹^,², DOU Bingde², LI Zhongling¹()

¹ Shaanxi Institute of Biological Agriculture, Xi’an 710043, Shaanxi, China
² Shaanxi Enzyme Engineer Technology Research Center, Lintong 710000, Shaanxi, China

Received:2023-05-15 Revised:2023-08-11 Online:2024-05-20 Published:2024-05-16

摘要/Abstract

摘要：

花青素作为一种天然的生物活性物质，在畜禽养殖业中应用广泛。综述了目前花青素的研究进展，并从绿色养殖角度阐述了花青素在畜禽养殖方面的应用情况，以及其对提高养殖效益的重要作用。推广使用花青素等饲料添加剂将成为未来畜禽养殖行业中的一个重要趋势，有助于实现养殖业的可持续发展。

关键词: 花青素, 饲料添加剂, 可持续, 畜禽养殖

Abstract:

Anthocyanin, as a natural bioactive substance, is widely used in the livestock and poultry breeding industry. This article reviews the current research progress on anthocyanins and discusses their application in livestock and poultry breeding from the perspective of green breeding and their important role in improving breeding benefits. The promotion of feed additives such as anthocyanins will become an important trend in the future livestock and poultry breeding industry, contributing to the industry's sustainable development.

Key words: anthocyanins, feed additives, sustainable, livestock and poultry breeding

韩姗姗, 岳淑宁, 张红艳, 戴佳锟, 窦秉德, 李忠玲. 天然抗氧化剂花青素在饲料添加剂中的应用[J]. 农学学报, 2024, 14(5): 60-66.

HAN Shanshan, YUE Shuning, ZHANG Hongyan, DAI Jiakun, DOU Bingde, LI Zhongling. Application of Natural Antioxidant Anthocyanins in Feed Additives[J]. Journal of Agriculture, 2024, 14(5): 60-66.

参考文献 73

[1]	WANG B, TANG X, MAO B, et al. Anti-aging effects and mechanisms of anthocyanins and their intestinal microflora metabolites[J]. Crit Rev Food Sci Nutr, 2022, 21:1-17.
[2]	祝志欣, 鲁迎青. 花青素代谢途径与植物颜色变异[J]. 植物学报, 2016, 51 (1):107-119. doi: 10.11983/CBB15059
[3]	李鲁华, 王忠妮, 任明见, 等. 谷类作物中植物激素调控花青素合成的研究进展[J]. 山地农业生物学报, 2022, 41(4):62-66.
[4]	严莉, 陈建伟, 王翠平, 等. 黑果枸杞WD40编码基因LrAN11的克隆及表达分析[J]. 核农学报, 2017, 31(11):2103-2112. doi: 10.11869/j.issn.100-8551.2017.11.2103
[5]	ZHAO M, LI J, ZHU L, et al. Identification and characterization of MYB-bHLH-WD40 regulatory complex members controlling anthocyanidin biosynthesis in blueberry fruits development[J]. Genes, 2019, 10(7):496-507.
[6]	LIU R, LAI B, HU B, et al. Identification of MicroRNAsand their target genes related to the accumulation of anthocyanins in Litchichinensis by high-throughput sequencing and degradome analysis[J]. Front. Plant Sci., 2017, 7:2059-2071.
[7]	WANG Y M, LIU WW, WANG X W, et al. MiR156 regulates anthocyanin biosynthesis through SPL targets and other microRNAs in poplar[J]. Hortic Res., 2020, 7:118-130.
[8]	AI P Y, XUE D L, WANG Y, et al. An efficient improved CRISPR mediated gene function analysis system established in Lycium ruthenicum Murr[J]. Ind. Crops Prod., 2023, 192:116142-116150.
[9]	TU M X, FANG J H, ZHAO R K, et al. CRISPR/Cas9-mediated mutagenesis of VvbZIP36 promotes anthocyanin accumulation in grapevine(Vitisvinifera)[J]. Hortic Res, 2022, 9:22-36.
[10]	BEUEL A K, JABLONKA N, HEESEL J, et al. LEDitSHAKE: A lighting system to optimize the secondary metabolite content of plant cell suspension cultures[J]. Sci Rep, 2021, 11:23353-23368.
[11]	盛建军, 李想, 何永美, 等. UV-B辐射对花青素合成代谢的影响及分子机理[J]. 植物生理学报, 2019, 55(7):949-958.
[12]	YU L J, SUN Y Y, ZHANG X, et al. ROS1 promotes low temperature-induced anthocyanin accumulation in apple by demethylating the promoter of anthocyanin-associated genes[J]. Hortic Res, 2022, 9:7-19.
[13]	YANG S N, MI L, WU J H, et al. Strategy for anthocyanins production: From efficient green extraction to novel microbial biosynthesis[J]. Crit. Rev. Food Sci. Nutr., 2022, 29:1-16.
[14]	李跃, 李国瑞, 陈永胜. 微生物代谢工程在花色苷生产过程中的应用现状和前景[J]. 食品科学, 2020, 41(13):260-266. doi: 10.7506/spkx1002-6630-20190618-202
[15]	李慧敏, 贾斌, 李霞, 等. 合成芳香族化合物的酵母底盘改造策略[J]. 中国生物工程杂志, 2022, 42(10):80-92.
[16]	李玲玲, 刘雪, 邱泽天, 等. 植物多酚的微生物合成[J]. 生物工程学报, 2021, 37(6):2050-2076.
[17]	EICHENBERGER M, HANSSON A, FISCHER D, et al. De novo biosynthesis of anthocyanins in Saccharomyces cerevisiae[J]. FEMS Yeast Res, 2018, 18(4):46-91.
[18]	JONES JA, VERNACCHIOV R, COLLINS SM, et al. Complete biosynthesis of anthocyanins using E. coli polycultures[J]. mBio, 2017, 8(3):621-630.
[19]	XU S, LI G J, ZHOU J W, et al. Efficient production of anthocyanins in Saccharomyces cerevisiae by introducing anthocyanin transporter and knocking out endogenous degrading enzymes[J]. Front. Bioeng. Biotechnol, 2022, 10:899182-899195.
[20]	BIANCONI M, CERIOTTI L, CUZZOCREA S, et al. Red carrot cells cultured in vitro are effective, stable, and safe ingredients for skin care, nutraceutical, and food applications[J]. Front. Bioeng. Biotechnol., 2020, 8:575079-575093.
[21]	BELWAL T, SINGH G, JEANDET P, et al. Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances[J]. Biotechnol. Adv., 2020, 43:107600-107620.
[22]	唐罗, 陈晓霞, 陈军, 等. 桑椹花青素加工稳定性及其应用研究进展[J]. 食品与发酵工业, 2022:1-13.
[23]	ZHENG J, DING C X, WANG L S, et al. Anthocyanins composition and antioxidant activity of wild Lycium ruthenicum Murr. from Qinghai-Tibet Plateau[J]. Food Chem., 2011, 126(3):859-865.
[24]	HE J R, YE S X, CORREIA P, et al. Dietary polyglycosylatedanthocyanins, the smart option? A comprehensive review on their health benefits and technological applications[J]. Compr. Rev. Food Sci. Food Saf., 2022, 21:3096-3128.
[25]	JOKIOJA J, YANG B R, LINDERBORG M K. Acylatedanthocyanins:A review on their bioavailability and effects on postprandial carbohydrate metabolism and inflammation[J]. Compr. Rev. Food Sci. Food Saf., 2021, 20:5570-5615.
[26]	赵祥杰, 杨文君, 杨荣玲, 等. 花色苷生物转化修饰的研究进展[J]. 生物技术通报, 2019, 35(10):205-211. doi: 10.13560/j.cnki.biotech.bull.1985.2019-0262
[27]	马久强, 王晓泽, 秦帅, 等. 黑枸杞中花青素的提取技术概述[J]. 江西化工, 2023, 39(1):5-8,12.
[28]	SINGH M C, PROBST Y, PRICE E W, et al. Relative comparisons of extraction methods and solvent composition for Australian blueberry anthocyanins[J]. J. Food Compos. Anal., 2022, 105:104232-104240.
[29]	FU X Z, DU Y L, ZOU L G, et al. Acidified glycerol as a one-step efficient green extraction and preservation strategy for anthocyanin from blueberry pomace:New insights into extraction and stability protection mechanism with molecular dynamic simulation[J]. Food Chem., 2022, 390:133226-133237.
[30]	DÍAZ-ÁLVAREZ R, CARULLO D, PATARO G, et al. Testing of a new high voltage electrical discharge generator prototype at high frequencies to assist anthocyanin extraction from blueberries[J]. Food Biosci., 2022, 50(Part A):102127-102138.
[31]	HU A J, HAO ST, ZHENG J, et al. Multi-frequency ultrasonic extraction of anthocyanins from blueberry pomace and evaluation of its antioxidant activity[J]. J. AOAC Int., 2021, 104:811-817.
[32]	ZHOU X, WU YT, WANG Y, et al. An efficient approach for the extraction of anthocyanins from Lyciumruthenicum using semi-continuous liquid phase pulsed electrical discharge system[J]. Innov.Food Sci. Emerg. Technol., 2022, 80:103099-103109.
[33]	DONG R H, TIAN J L, HUANG Z Y, et al. Intermolecular binding of blueberry anthocyanins with water-soluble polysaccharides: Enhancing their thermo stability and antioxidant abilities[J]. Food Chem., 2023, 410:135375-135388.
[34]	WANG Y P, FU J X, YANG D. In situ stability of anthocyanins in Lycium ruthenicum Murray[J]. Molecules, 2021, 26(23):7073-7079.
[35]	MUCHEB M, SPEERS R A, RUPASINGHEHP V. Storage temperature impacts on anthocyanins degradation, color changes and haze development in juice of "Merlot" and "Ruby" grapes(Vitisvinifera)[J]. Front. Nutr., 2018, 5:100-109.
[36]	LI J F, LI Z P, MA S S, et al. Enhancement of anthocyanins extraction from haskap by cold plasma pretreatment[J]. Innov.Food Sci. Emerg. Technol., 2023, 84:103294-103304.
[37]	TAN C, DADMOHAMMADI Y, LEE M C, et al. Combination of copigmentation and encapsulation strategies for the synergistic stabilization of anthocyanins[J]. Compr Rev Food Sci Food Saf., 2021, 20(4):3164-3191.
[38]	DUDEK A, SPIEGEL M, STRUGAŁA-DANAK P, et al. Analytical and theoretical studies of antioxidant properties of chosen anthocyanins; a structure-dependent relationships[J]. Int. J. Mol. Sci., 2022, 23(10):5432-5450.
[39]	MA Y, FENG Y H, DIAOT W, et al. Experimental and theoretical study on antioxidant activity of the four anthocyanins[J]. J. Mol. Struct., 2020, 1204:127509-127536.
[40]	李煦, 白雪晴, 刘长霞, 等. 天然花青素的抗氧化机制及功能活性研究进展[J]. 食品安全质量检测学报, 2021, 12(20):8163-8171.
[41]	HERRERA-BALANDRANO D D, CHAI Z, HUTABARAT R P, et al. Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPKactivation: In vitro and in vivo studies[J]. Redox Biol., 2021, 46:102100-102113.
[42]	XIE L H, SU H M, SUN C D, et al. Recent advances in understanding the anti-obesity activity of anthocyanins and their biosynthesis in microorganisms[J]. Trends Food Sci. Technol., 2018, 72:13-24.
[43]	PENG Y J, YAN Y M, WAN P, et al. Gut microbiota modulation and anti-inflammatory properties of anthocyanins from the fruits of Lycium ruthenicum Murray in dextran sodium sulfate-induced colitis in mice[J]. Free Radic. Biol. Med., 2019, 136:96-108.
[44]	EKERM E, AABY K, BUDICLETO I, et al. A review of factors affecting anthocyanin bioavailability: Possible implications for the inter-individual variability[J]. Foods, 2020, 9(1):2-20.
[45]	KALT W, MCDONALD J, VINQVIST-TYMCHUK M, et al. Human anthocyanin bioavailability: Effect of intake duration and dosing[J]. Food Funct., 2017, 8:4563-4569. doi: 10.1039/c7fo01074e pmid: 29115354
[46]	DI LORENZO C, COLOMBO F, BIELLA S, et al. Polyphenols and human health: The role of bioavailability[J]. Nutrients, 2021, 13(1):273-303.
[47]	LI Y. Synthesis of porous starch microgels for the encapsulation, delivery and stabilization of anthocyanins[J]. J. Food Eng., 2021, 302:110552-110561.
[48]	JIANG Z Y, ZHAO S J, FAN Z Y, et al. A novel all-natural (collagen + pectin)/chitosan aqueous two-phase microcapsule with improved anthocyanin loading capacity[J]. Food Hydrocolloids, 2023, 134:107984-107994.
[49]	HERRERA-BALANDRANOD D, CHAI Z, BETA T, et al. Blueberry anthocyanins: An updated review on approaches to enhancing their bioavailability[J]. Trends Food Sci. Technol., 2021, 118(Part B), 808-821.
[50]	XIEC J, HUANG M G, YING R F, et al. Olive pectin-chitosan nanocomplexes for improving stability and bioavailability of blueberry anthocyanins[J]. Food Chem., 2023, 417:135798-135823.
[51]	ZHAO J C, YU J, ZHI Q, et al. Anti-aging effects of the fermented anthocyanin extracts of purple sweet potato on Caenorhabditi selegans[J]. Food Funct., 2021, 12:12647-12658.
[52]	BARIEXCA T, EZDEBSKI J, REDAN BW, et al. Pure polyphenols and cranberry juice high in anthocyanins increase antioxidant capacity in animal organs[J]. Foods, 2019, 8(8):340-350.
[53]	周迪, 王胤晨, 田兴舟, 等. 花青素增强反刍动物抗氧化性能作用机制的研究[J]. 畜牧兽医学报, 2019, 50(8):1536-1544.
[54]	CHANGXING L, CHENLING M, ALAGAWANY M, et al. Health benefits and potential applications of anthocyanins in poultry feed industry[J]. World's Poult. Sci. J., 2018, 74(2):251-264.
[55]	EMESE T, PETER F, GABOR F, et al. Nutraceuticals induced changes in the broiler gastrointestinal tract microbiota[J]. mSystems, 2021, mSystems, 6(2):1-25.
[56]	MA Y, DING S J, FEI Y Q, et al. Antimicrobial activity of anthocyanins and catechins against foodborne pathogens Escherichia coli and Salmonella[J]. Food Control, 2019, 106:106712-106720.
[57]	KHAN M S, IKRAM M, PARK J S, et al. Gut microbiota, its role in induction of Alzheimer's disease pathology, and possible therapeutic interventions: Special focus on anthocyanins[J]. Cells, 2020, 9(4):853-874.
[58]	LINH N V, NGUYEN D V, KHONGDEE N, et al. Influence of black rice (Oryzasativa L.) bran derived anthocyanin-extract on growth rate, immunological response, and immune-antioxidant gene expression in Nile tilapia (Oreochromis niloticus) cultivated in a biofloc system[J]. Fish Shellfish Immunol., 2022, 128:604-611.
[59]	MINH T N S, SIWAPORN P, THOMAS J S, et al. Growth performance, blood biochemical indices, rumen bacterial community, and carcass characteristics in goats fed anthocyanin-rich black cane silage[J]. Front. Vet. Sci., 2022, 9:880838-880848.
[60]	PATINDRA A R P, MINH T N S, SIWAPORN P, et al. Dietary inclusion of anthocyanin-rich black cane silage treated with ferrous sulfate heptahydrate reduces oxidative stress and promotes tender meat production in goats[J]. Front. Vet. Sci., 2022, 9:969321-969333.
[61]	SUONGN T M, PAENGKOUM S, PURBAR A P, et al. Optimizing anthocyanin-rich black cane (Saccharumsinensisrobx.) silage for ruminants using molasses and iron sulphate: A sustainable alternative[J]. Fermentation, 2022, 8(6):248-269.
[62]	张超, 史红丽, 戴佳锟, 等. 鲜食黑糯玉米新品种陕K8143的选育[J]. 中国种业, 2023, 3:106-108.
[63]	TIAN XZ, PAENGKOUM P, PAENGKOUM S, et al. Comparison of forage yield, silage fermentative quality, anthocyanin stability, antioxidant activity, and in vitro rumen fermentation of anthocyanin-rich purple corn (Zea mays L.) stover and sticky corn stover[J]. J IntegrAgr, 2018, 17(9):2082-2095.
[64]	LI J X, ZHOU D, LI H, et al. Effect of purple corn extract on performance, antioxidant activity, egg quality, egg amino acid, and fatty acid profiles of laying hen[J]. Front. Vet. Sci., 2023, 9:1083842-1083853.
[65]	ANTUNOVIĆ Z, NOVOSELEC J, KLIRŠALAVARDIĆ Ž, et al. Influence of red corn rich in anthocyanins on productive traits, blood metabolic profile, and antioxidative status of fattening lambs[J]. Animals, 2022, 12(5):612-624.
[66]	HOSODA K, ERUDEN B, MATSUYAMA H, et al. Effect of anthocyanin-rich corn silage on digestibility, milk production and plasma enzyme activities in lactating dairy cows[J]. Anim. Sci. J., 2012, 83(6):453-459. doi: 10.1111/j.1740-0929.2011.00981.x pmid: 22694328
[67]	TIAN X, LU Q. Anthocyanins in dairy cow nutrition: A review[J]. Agriculture, 2022, 12(11):1806-1819.
[68]	WEI L, GOMAA W, AMETAJ B, et al. Feeding red osier dogwood (Cornussericea) to beef heifers fed a high-grain diet affected feed intake and total tract digestibility[J]. Anim. Feed Sci. Technol, 2019, 247:83-91.
[69]	PROMMACHART R, CHERDTHONG A, NAVANUKRAW C, et al. Effect of dietary anthocyanin-extracted residue on meat oxidation and fatty acid profile of male dairy cattle[J]. Animals, 2021, 11(2):322-340.
[70]	GAO J, ZHAO G Y. Potentials of using dietary plant secondary metabolites to mitigate nitrous oxide emissions from excreta of cattle: Impacts, mechanisms, and perspectives[J]. Anim. Nutr., 2022, 9:327-334.
[71]	LI D T, WANG P P, LUO Y H, et al. Health benefits of anthocyanins and molecular mechanisms: Update from recent decade[J]. Crit. Rev. Food Sci. Nutr., 2017, 57:1729-1741. doi: 10.1080/10408398.2015.1030064 pmid: 26192537
[72]	YANG C, CHOWDHURY MAK, HOU Y, et al. Phytogenic compounds as alternatives to in-feed antibiotics: Potentials and challenges in application[J]. Pathogens. 2015, 4:137-156. doi: 10.3390/pathogens4010137 pmid: 25806623
[73]	ABDELLI N, SOLÀ-ORIOL D, PÉREZ J F. Phytogenic feed additives in poultry: Achievements, prospective and challenges[J]. Animals(Basel), 2021, 11(12):3471-3497.

天然抗氧化剂花青素在饲料添加剂中的应用

Application of Natural Antioxidant Anthocyanins in Feed Additives

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 73

相关文章 15

编辑推荐

Metrics

本文评价

关于本刊

作者中心

审者中心

在线期刊

联系我们

[1]	韩姗姗, 李忠玲, 张红艳, 戴佳锟, 窦秉德, 岳淑宁. 探究复合菌剂在奶牛粪污处理中的应用进展[J]. 农学学报, 2024, 14(4): 66-71.
[2]	殷红, 张红艳, 张强, 韩姗姗. 后抗时代发酵中药在动物生产中的应用[J]. 农学学报, 2023, 13(11): 67-72.
[3]	赵玲, 张华. 乡村振兴视角下文物旅游高质量发展的问题与对策[J]. 农学学报, 2023, 13(1): 96-100.
[4]	宋洁, 何洁, 秦怡峰, 李德华, 吴江, 赵晟, 梁译丹, 刘晶晶, 李向阳, 王越茂. 云南烟叶可持续发展规范(STP)推广成效与启示[J]. 农学学报, 2022, 12(8): 68-72.
[5]	杨晓辉, 杜荣, 秦瑞敏, 徐满厚. 基于主成分分析的山西省集中连片特困区农业经济发展评价[J]. 农学学报, 2021, 11(8): 116-124.
[6]	吕婉莹, 贾冬梅, 胡云峰, 陈君然. 贮运条件对草莓主要色素成分稳定性的影响[J]. 农学学报, 2021, 11(6): 73-77.
[7]	何兰, 姜卫兵, 宋居宇. 试论中国重要农业文化遗产的可持续发展[J]. 农学学报, 2021, 11(2): 79-85.
[8]	马晶, 杜勇, 陈鹏飞, 魏政, 刘荣志. 黑土地上的农业绿色科技发展[J]. 农学学报, 2020, 10(1): 93-96.
[9]	黄国勤. 论生态农场建设与发展[J]. 农学学报, 2019, 9(4): 95-100.
[10]	黄国勤. 农业可持续发展的研究与实践[J]. 农学学报, 2019, 9(3): 79-88.
[11]	张海欧,张海欧<sub>. 浅谈不同材料在盐渍化土壤改良中的应用[J]. 农学学报, 2019, 9(12): 39-42.
[12]	黄铢玉,方龙香,宋超,范立民,孟顺龙,裘丽萍,陈家长. 抗生素恩诺沙星及其代谢产物在渔业水体中迁移转化规律的研究进展[J]. 农学学报, 2019, 9(11): 57-62.
[13]	李顺国,刘斐,刘猛,刁现民. 新时期我国谷子产业发展技术需求与展望[J]. 农学学报, 2018, 8(6): 96-100.
[14]	闫丽沙. 山西省交城县土地开发利用现状及可持续利用对策[J]. 农学学报, 2018, 8(5): 81-84.
[15]	侯新村,范希峰,朱毅,岳跃森,武菊英. 作物秸秆生物质原料可持续利用模式探究[J]. 农学学报, 2018, 8(4): 32-38.