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Effect of multiple time point sampling on the sensitivity of the dexamethasone suppression test

Published Online:https://doi.org/10.1176/ajp.140.7.909

Dexamethasone suppression test sensitivity in 188 patients was 61.6% when cortisol was measured at six time points and 48.5% when cortisol was measured twice. More patients had abnormal cortisol levels at 8:00 p.m. than at 4:00 p.m. or 10:00 p.m.

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