The objective of this study was to determine the epidemiological characteristics of sensitization to Aspergillus in these atopic sickle cell patients who present respiratory disorders unrelated to taking NSAIDs. This is a prospective study with a descriptive and analytical aim which was conducted at the University Hospital Center (CHU) of Cocody (Abidjan). It took place from September 2017 to May 2018 on 117 atopic sickle cell disease patients, with no known history of allergy to aeroallergens, to any foods or to occupational allergens. These patients were interviewed and clinically examined for an atopic site. They were subsequently subjected to skin tests. Statistical analyzes were performed using Epi info 6.0 software using Fisher's test and odds ratio. The significance level was located at an odds ratio greater than 1. The comparison of the percentages was carried out by Fisher's test with a significance level p = 0.05. The majority of patients with sensitization to Aspergillus mix were over 15 years of age, with a predominance of women (Sex ratio: 0.56). Neither sex nor age appeared to influence the state of sensitization in our study (p> 0.05). The overall prevalence of sensitization to Aspergillus mix was 7.7%. Our results correlated asthma severity with sensitization to Aspergillus mix (p<0.05). However, there was no significant correlation between severity of allergic rhinitis and sensitization to Apergillus mix. This study confirms the low prevalence of sensitization to Aspergillus mix. Allergy to Aspergillus mix is an uncommon phenomenon in sickle cell patients but its monitoring in this population should be given special attention as it is subject to many complications.
| Published in | International Journal of Immunology (Volume 9, Issue 1) |
| DOI | 10.11648/j.iji.20210901.11 |
| Page(s) | 1-5 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Sensitization, Aspergillus Mix, Atopic, Sickle Cell Disease
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APA Style
Adou Adjoumanvoule Honoré, Kabore Saydou, Dassé Sery Romuald, Yeboah Opong Richard, Goran-Kouacou Amah Patricia, et al. (2021). Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire. International Journal of Immunology, 9(1), 1-5. https://doi.org/10.11648/j.iji.20210901.11
ACS Style
Adou Adjoumanvoule Honoré; Kabore Saydou; Dassé Sery Romuald; Yeboah Opong Richard; Goran-Kouacou Amah Patricia, et al. Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire. Int. J. Immunol. 2021, 9(1), 1-5. doi: 10.11648/j.iji.20210901.11
AMA Style
Adou Adjoumanvoule Honoré, Kabore Saydou, Dassé Sery Romuald, Yeboah Opong Richard, Goran-Kouacou Amah Patricia, et al. Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire. Int J Immunol. 2021;9(1):1-5. doi: 10.11648/j.iji.20210901.11
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author = {Adou Adjoumanvoule Honoré and Kabore Saydou and Dassé Sery Romuald and Yeboah Opong Richard and Goran-Kouacou Amah Patricia and Siransy Kouabla Liliane and N’Guessan Koffi and Assi Aya Ursule Aniela and Memel Lasme Roselle Charline and Zaho Ouleon Lea and Yassongui Mamadou Sekongo},
title = {Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire},
journal = {International Journal of Immunology},
volume = {9},
number = {1},
pages = {1-5},
doi = {10.11648/j.iji.20210901.11},
url = {https://doi.org/10.11648/j.iji.20210901.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20210901.11},
abstract = {The objective of this study was to determine the epidemiological characteristics of sensitization to Aspergillus in these atopic sickle cell patients who present respiratory disorders unrelated to taking NSAIDs. This is a prospective study with a descriptive and analytical aim which was conducted at the University Hospital Center (CHU) of Cocody (Abidjan). It took place from September 2017 to May 2018 on 117 atopic sickle cell disease patients, with no known history of allergy to aeroallergens, to any foods or to occupational allergens. These patients were interviewed and clinically examined for an atopic site. They were subsequently subjected to skin tests. Statistical analyzes were performed using Epi info 6.0 software using Fisher's test and odds ratio. The significance level was located at an odds ratio greater than 1. The comparison of the percentages was carried out by Fisher's test with a significance level p = 0.05. The majority of patients with sensitization to Aspergillus mix were over 15 years of age, with a predominance of women (Sex ratio: 0.56). Neither sex nor age appeared to influence the state of sensitization in our study (p> 0.05). The overall prevalence of sensitization to Aspergillus mix was 7.7%. Our results correlated asthma severity with sensitization to Aspergillus mix (p<0.05). However, there was no significant correlation between severity of allergic rhinitis and sensitization to Apergillus mix. This study confirms the low prevalence of sensitization to Aspergillus mix. Allergy to Aspergillus mix is an uncommon phenomenon in sickle cell patients but its monitoring in this population should be given special attention as it is subject to many complications.},
year = {2021}
}
TY - JOUR T1 - Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire AU - Adou Adjoumanvoule Honoré AU - Kabore Saydou AU - Dassé Sery Romuald AU - Yeboah Opong Richard AU - Goran-Kouacou Amah Patricia AU - Siransy Kouabla Liliane AU - N’Guessan Koffi AU - Assi Aya Ursule Aniela AU - Memel Lasme Roselle Charline AU - Zaho Ouleon Lea AU - Yassongui Mamadou Sekongo Y1 - 2021/01/12 PY - 2021 N1 - https://doi.org/10.11648/j.iji.20210901.11 DO - 10.11648/j.iji.20210901.11 T2 - International Journal of Immunology JF - International Journal of Immunology JO - International Journal of Immunology SP - 1 EP - 5 PB - Science Publishing Group SN - 2329-1753 UR - https://doi.org/10.11648/j.iji.20210901.11 AB - The objective of this study was to determine the epidemiological characteristics of sensitization to Aspergillus in these atopic sickle cell patients who present respiratory disorders unrelated to taking NSAIDs. This is a prospective study with a descriptive and analytical aim which was conducted at the University Hospital Center (CHU) of Cocody (Abidjan). It took place from September 2017 to May 2018 on 117 atopic sickle cell disease patients, with no known history of allergy to aeroallergens, to any foods or to occupational allergens. These patients were interviewed and clinically examined for an atopic site. They were subsequently subjected to skin tests. Statistical analyzes were performed using Epi info 6.0 software using Fisher's test and odds ratio. The significance level was located at an odds ratio greater than 1. The comparison of the percentages was carried out by Fisher's test with a significance level p = 0.05. The majority of patients with sensitization to Aspergillus mix were over 15 years of age, with a predominance of women (Sex ratio: 0.56). Neither sex nor age appeared to influence the state of sensitization in our study (p> 0.05). The overall prevalence of sensitization to Aspergillus mix was 7.7%. Our results correlated asthma severity with sensitization to Aspergillus mix (p<0.05). However, there was no significant correlation between severity of allergic rhinitis and sensitization to Apergillus mix. This study confirms the low prevalence of sensitization to Aspergillus mix. Allergy to Aspergillus mix is an uncommon phenomenon in sickle cell patients but its monitoring in this population should be given special attention as it is subject to many complications. VL - 9 IS - 1 ER -
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