Progress of Digestive Endoscopy
Online ISSN : 2187-4999
Print ISSN : 1348-9844
ISSN-L : 1348-9844
症例
内分泌細胞微小胞巣を伴う胃管状腫瘍の1例
宮澤 祥一宇野 昭毅龍 芯依西尾 みどり中村 由紀川島 志布子塩沢 雄二永井 晋太郎田村 彰教上原 俊樹中村 仁美佐藤 秀樹原澤 尚登水野 滋章松井 輝明森山 光彦
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2013 年 82 巻 1 号 p. 128-129

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A flat elevated whitish lesion of 5 mm in diameter was identified in the greater curvature of the antrum in a 73-year-old woman. The biopsy specimen was diagnosed histologically as tubular adenoma. Two years later, endoscopic re-examination was performed and a biopsy revealed endocrine cell micronests (ECMs) at the base of the tubular adenoma. One of ECMs measured greater than 200μm, suggestive of so-called minute carcinoid. ECMs and some cells in the tubular adenoma were positive for synaptophysin and chromogranin A. The tumor was suspected to be a composite adenoma-carcinoma tumor and was treated by endoscopic mucosal resection. The resected specimen was diagnosed as well-differentiated tubular adenocarcinoma with ECMs at the base of the tubular portion. This case report provides important information on histogenesis and differentiation of gastric neoplasms with endocrine features.

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© 2013 一般社団法人 日本消化器内視鏡学会 関東支部
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