A case of primary pulmonary aspergillosis of a 29-year-old femal was reported. An increasing number of human infections with Aspergillus have been reported recently. In the majority of the cases, however, the diagnosis is determined first by the histolo gical examination after autopsy. However in this case pulmonary aspergillosis was suspected because of the positive culture findings of Aspergillus fumigatus from the sputum, urine and blood of the patient during her lifetime and the diagnosis was confi rmed at autopsy by the demonstration of Aspergilli in both the caverns and the involved pulmonary parenchyma of this case.
It is generally accepted that pulmonary aspergillosis has a mild course, the main symptom being only hemoptysis. It seems therefore to be much interesting that the clinical course and the change of X-ray picture in this case were relatively acute.
The large doses of several kinds of chemotherapeutics administrated to this case: might show some influence upon the incidence of aspergillosis.