Yangchen Fu
ABSTRACT
Super-harmonics (SH) only come from contrast agents (CA), and the clutter-free SH imaging (SHI) has higher quality in ultrasound CA imaging. How to better separate the SH from echo signals is a key issue to improve the SHI of the CA. The existing three algorithms all have some limitations, the arrival artifact of pulse inversion (PI) method, the inflexible parameters of high pass filter (HPF) method and the noise residue of complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) method. In this study, the improved complete ensemble empirical mode decomposition with adaptive noise adaptive decomposition of adaptive noise (ICEEMDAN) method is proposed to improve the quality of the SHI. The CA echo signals from computer simulations and rabbit kidney experiments are decomposed by the ICEEMDAN to obtain a set of intrinsic mode functions (IMF), and then the SH are obtained by adaptive decomposition according to the IMF spectra. The results show that the SHI based on the ICEEMDAN has clearer contours, less interference, and higher image contrast. For the rabbit kidney experiments, the contrasts, contrast-to-noise ratios (CNR), and tissue-to-clutter ratios (TCR) of the ICEEMDAN-based SHI are averagely increased by 43.03%, 27.40% and 33.13%, compared with those based on the PI, HPF and CEEMDAN methods. Therefore, the ICEEMDAN method proposed in this paper has a better effect on separating the SH and can improve the performance of the SHI.
- Maresca D, Skachkov I, Renaud G, Imaging microvasculature with contrast-enhanced ultra-harmonic ultrasound. Ultrasound in Medicine & Biology. 2014, 40(6):1318–1328.Google Scholar
Cross Ref
- Maresca D, Renaud G, van Soest G, Contrast-enhanced intravascular ultrasound pulse sequences for bandwidth-limited transducers. Ultrasound in Medicine & Biology. 2013, 39(4):706–713.Google ScholarCross Ref
- Daeichin V, Bosch J G, Needles A, Sub-harmonic, non-linear fundamental and ultra-harmonic imaging of micro bubble contrast at high frequencies. Ultrasound in Medicine & Biology. 2015, 41(2):486–497.Google ScholarCross Ref
- Wada H, Yasu T, Sakakura K, Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction. Heart & Vessels, 2014, 29(3):308-312.Google ScholarCross Ref
- Eisenbrey J R, Dave J K, Halldorsdottir V G, Simultaneous gray scale and sub-harmonic ultrasound imaging on a modified commercial scanner. Ultrasonic, 2011, 51(8):890-897.Google ScholarCross Ref
- Strobel D, Raeker S, Martus P, Phase inversion harmonic imaging versus contrast-enhanced power Doppler sonography for the characterization of focal liver lesions . International Journal of Cool-rectal Disease, 2003, 18(1):63-72.Google Scholar
- Chinda S, Pomchai P. Pulse inversion linear band pass filter for detecting sub-harmonic from micro bubbles. 2011 Eighth International Joint Conference on Computer Science and Software Engineering, 2011, 143-148.Google Scholar
- Eisenbrey J R, Sridharan A, Liu J, Recent Experiences and Advances in Contrast-Enhanced Sub-harmonic Ultrasound. Biological Medicine Research International, 2015, 2015:640397.Google Scholar
- Torres M E, Colominas M A, Schlotthauer G, Complete ensemble empirical mode decomposition with adaptive noise. IEEE International Conference on Acoustics, 2011, 125:4144-4147.Google ScholarCross Ref
- Colominas M, Schlotthauer G, Torres M, Improved complete ensemble EMD: A suitable tool for biomedical signal processing, Biomedical Signal Processing and Control, 2014, 39:19-29.Google ScholarCross Ref
- Huang N E, Shen Z, Long S R, The empirical mode decomposition and the Hilbert spectrum for nonlinear and no stationary time series analysis. Proceedings of Royal Society of London, Series A: Mathematical, Physical & Engineering Sciences, 1998, 454(1971):903–995.Google ScholarCross Ref
- Varray F, Basset O, Tortoli P, CREANUIS: a non-linear radio frequency ultrasound image simulator. Ultrasound in Medicine & Biology, 2013, 39(10):1915-1924.Google ScholarCross Ref
- Varray F, Ramalli A, Cachard C, Fundamental and second-harmonic ultrasound field computation of inhomogeneous nonlinear medium with a generalized angular spectrum method. Ultrasonic Ferroelectrics & Frequency Control IEEE Transactions on, 2011, 58(7):1366- 1376.Google ScholarCross Ref
- K.E. Morgan, J. S. Allen, P. A. Dayton, J. E. Chomas, A. L. Klibanov, and K. W. Ferrara. Experimental and theoretical evaluation of micro bubble behavior: effect of transmitted phase and bubble size. Ultrasonic Ferroelectrics & Frequency Control IEEE Transactions on, 2000, 47(6):1494-509.Google ScholarCross Ref
- Van Wijk M C, Thijssen J M. Performance testing of medical ultrasound equipment: fundamental vs. harmonic mode. Ultrasonic, 2002, 40(1):585-591.Google ScholarCross Ref
Index Terms
- Improved Super-harmonic Imaging of Ultrasound Contrast Agents Based on ICEEMDAN
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