Obstetric hemorrhage has a high mortality rate, with massive hemorrhage commonly leading to a coagulopathic condition. Therefore, prompt hemostasis is essential for obstetric hemorrhage. However, an emergency peripartum hysterectomy has a high risk of maternal morbidity and fatality. On the other hand, uterine artery embolization (UAE) is an effective treatment for dealing with obstetric hemorrhages, because it is minimally invasive, has a high success rate and can preserve fertility. In a coagulopathic condition, the recurrent hemorrhage rate is higher for gelatin sponge particles (GSPs) than for N-butyl cyanoacrylate (NBCA). Recently, UAE with NBCA is becoming more frequently performed clinically for postpartum hemorrhages. We report here clinical UAE performed in our hospital, and animal research results on the degree of uterine damage caused by UAE with GSPs and NBCA in swine.