We report a 5-year-old girl with acute lymphoblastic leukemia (ALL) in the second remission who was treated with syngeneic bone marrow transplantation (BMT), followed by the maintenance chemotherapy. She was given marrow transplant from her identical twin after cyclophosphamide (60 mg/kg×2) and fractionated total body irradiation (2Gy×5). Fifteen weeks later, she was placed on the maintenance chemotherapy with 6MP, methotrexate, prednisolone and vincristine.
Pancytopenia and immunologic abnormalities such as imbalance of T lymphocyte subsets and suppressed in vitro immunoglobulin production were promptly recovered. She has survived for more than twelve months in complete remission.
