Letters
Calcium and heart attacks
Authors’ reply
BMJ 2010; 341 doi: https://doi.org/10.1136/bmj.c4998 (Published 15 September 2010) Cite this as: BMJ 2010;341:c4998
- Mark J Bolland, senior research fellow1,
- Alison Avenell, clinical senior lecturer2,
- John A Baron, professor of medicine3,
- Andrew Grey, associate professor of medicine1,
- Ian R Reid, professor of medicine1,
- Graeme S MacLennan, senior research fellow2,
- Greg D Gamble, research fellow1
- 1Department of Medicine, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand
- 2Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD
- 3Departments of Medicine, and Community and Family Medicine, Dartmouth Medical School, Hanover, NH 03755, USA
- i.reid{at}auckland.ac.nz
As Dawson-Hughes and Heiss and colleagues suggest,1 2 our results are not generalisable to combined calcium and vitamin D treatment. Investigation of this treatment should be a high priority. In one large study in our meta-analysis the risks of myocardial infarction and stroke with calcium and vitamin D were similar to those with calcium alone.3 The WHI study reported no increase in cardiovascular risk in women randomised to calcium and vitamin D,4 but >50% of participants …
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