耳鼻と臨床
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
耳鳴・感音難聴に対するMethyl-B12の臨床効果
小田 恂, 野村 恭也, 牛嶋 達次郎, 渡辺 勇, 鳥山 稔, 佐藤 恒正, 冨田 寛, 菊池 恭三, 本多 芳男, 原田 勇彦, 山口 宏也, 神崎 仁, 細谷 睦, 小松崎 篤, 岡本 途也, 堀内 和之, 高橋 文雄, 猪 忠彦, 古賀 慶次郎, 河村 正三, 奥田 稔, 弓削 庫太, 山田 文則, 宮川 晃一, 岩村 忍, 藤岡 正勝, 小林 武夫, 大西 信次郎, 石井 哲夫, 荒牧 元, 小寺 一興, 安部 治彦, 堤 昌己, 村主 好弘
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キーワード: 耳鳴, 感音難聴, メチルコバラミン
ジャーナル フリー

1985 年 31 巻 6 号 p. 1196-1204

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Therapeutic effects of methyl B12 for subjective tinnitus and sensorineural hearing loss were investigated on 576 cases in the Tokyo district. Out of them, 560 cases (773 ears) were patients suffering from subjective tinnitus and 430 cases (637 ears) were patients with sensorineural hearing loss. Methyl B12 was administrated to each patients 1500μg per a day. On the fourth and 8th week after treatment, the patients were asked whether or not their tinnitus varried and were tested by pure tone audiometry. The patients with acute onset on tinnitus (226 cases) showed the most effective result. Thirty one per cent of them had been aware of disappearance or diminishing of their annoying tinnitus. In acute sensorineural hearing loss (128 cases), 26% of the patients had an improvement in their audiogram. On the other hand, in non-acute cases of tinnitus (285 cases) and hearing loss (228 cases), Methyl B12 seemed to be ineffective. Of all patients considered, Methyl B12 were effective in 28% of all tinnitus patinets and in 13% of patients of sensorineural hearring impairment.

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