A Case of Stage 0 Pancreatic Adenocarcinoma (High-grade PanIN) Incidentally Detected on Routine Screening Ultrasonography

Sachiko Tanaka; Mikako Miyamoto; Anri Sugimoto; Hiromi Nishiyama; Tomomi Nakagawa; Ayano Hara; Chika Yoshino; Rena Takakura; Hiroyuki Uehara

doi:10.11320/ningendockitn.8.1_59

Case Report

A Case of Stage 0 Pancreatic Adenocarcinoma (High-grade PanIN) Incidentally Detected on Routine Screening Ultrasonography

Sachiko Tanaka, Mikako Miyamoto, Anri Sugimoto, Hiromi Nishiyama, Tomomi Nakagawa, Ayano Hara, Chika Yoshino, Rena Takakura, Hiroyuki Uehara

Author information

Sachiko Tanaka
Osaka Center for Cancer and Cardiovascular Disease Prevention
Mikako Miyamoto
Osaka Center for Cancer and Cardiovascular Disease Prevention
Anri Sugimoto
Osaka Center for Cancer and Cardiovascular Disease Prevention
Hiromi Nishiyama
Osaka Center for Cancer and Cardiovascular Disease Prevention
Tomomi Nakagawa
Osaka Center for Cancer and Cardiovascular Disease Prevention
Ayano Hara
Osaka Center for Cancer and Cardiovascular Disease Prevention
Chika Yoshino
Osaka Center for Cancer and Cardiovascular Disease Prevention
Rena Takakura
Health Administration Center, Sumitomo Hospital
Hiroyuki Uehara
Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute

Keywords: stage 0 pancreatic cancer, main pancreatic duct dilatation, screening ultrasonography, irregular internal line of the pancreatic duct

JOURNAL FREE ACCESS

2021 Volume 8 Issue 1 Pages 59-63

DOI https://doi.org/10.11320/ningendockitn.8.1_59

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Abstract

Most cases of pancreatic cancer are diagnosed during the advanced stage, resulting in a low long-term survival rate. Thus, early detection is important to achieve a favorable prognosis. We present herein a case of stage 0 (in situ) pancreatic adenocarcinoma incidentally detected on routine screening ultrasonography during a health check-up. Slight dilatation of the main pancreatic duct was detected from the body to the tail of the pancreas of an otherwise healthy male patient. Since this finding is a possible sign of pancreatic cancer, the sonographer traced the duct downstream with a magnified image. No pancreatic duct obstruction or nodules were detected. However, the internal line of the main pancreatic duct (MPD) was irregular, and a debris-like faint hypoechoic region was observed within the MPD at the head of the pancreas. Intraductal proliferation of cancer was suspected, and the diagnosis of stage 0 pancreatic adenocarcinoma (high-grade PanIN) was confirmed with pancreatic juice cytology. The patient underwent surgical resection and is currently alive without recurrence 6 years after the surgery.

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