Experimental approach to sensorineural hearing loss

S. Inafuku; I. Takimoto; I. Inuzuka; T. Enatsu; K. Sugiyama; T. Morimoto; H. Kawade; M. Hara; K. Yoshikawa; K. Ohshima

doi:10.11289/otoljpn1981.13.152

S. Inafuku, I. Takimoto, I. Inuzuka, T. Enatsu, K. Sugiyama, T. Morimoto, H. Kawade, M. Hara, K. Yoshikawa, K. Ohshima

Author information

S. Inafuku
Department of Otorhinolaryngology, Aichi Medical University
I. Takimoto
Department of Otorhinolaryngology, Aichi Medical University
I. Inuzuka
Department of Otorhinolaryngology, Aichi Medical University
T. Enatsu
Department of Otorhinolaryngology, Aichi Medical University
K. Sugiyama
Department of Otorhinolaryngology, Aichi Medical University
T. Morimoto
Department of Otorhinolaryngology, Aichi Medical University
H. Kawade
Department of Otorhinolaryngology, Aichi Medical University
M. Hara
Department of Otorhinolaryngology, Aichi Medical University
K. Yoshikawa
Department of Otorhinolaryngology, Aichi Medical University
K. Ohshima
Department of Otorhinolaryngology, Aichi Medical University

JOURNAL FREE ACCESS

1982 Volume 13 Issue 1 Pages 152-153

DOI https://doi.org/10.11289/otoljpn1981.13.152

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Abstract

A chronic relapsing form of experimental allergic encephalomyelitis and neuritis was induced by single sensitization of immature and adult Hartley guinea pigs. Clinically, the disease was characterized by relapses. Among them, a few animals showed a severe hearing loss. Histological studies of their cochleae showed a severe loss of ganglion cells and hair cells. The organ of Corti was atrophied but stria vascularis was no changes. There was granular precipitate in scala media and scala tympani.

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