A 22-year-old woman with ulcerative colitis has been followed up for two years since the establishment of the diagnosis; she has been asymptomatic for the past one year, under treatment with sulfasalazine 2g/day. She was admitted to our hospital with sudden onset of fever and diarrhea. In the laboratory findings, inflammatory parameters such as Creactive protein and ESR were elevated. Double contrast study of colon showed multiple barium flecks and edematous mucosa in the proximal portion of ascending colon and cecum. However the remaining colon and rectum showed coarse mucosal pattern alone. Colonoscopy showed multiple shallow ulcers in cecum and proximal ascending colon and the findings of quiescent colitis from rectum to transverse colon. The cultures of stool were positive for Salmonella isutanbul. Thus, she was diagnosed as salmonella colitis associated with inactive ulcerative colitis. Her symptoms and inflammatory signs disappeared after antibiotics were administered. Salmonella infection associated with ulcerative colitis has been rarely reported in Japan. This ease was the 7th one during the fast 23 years.