ENDOSCOPIC AND PATHOLOGICAL FEATURES OF UPPER GASTROINTESTINAL CARCINOID TUMORS

Shinji NASU; Shigeaki YOSHIDA; Daizoh SAITOH; Hajime YAMAGUCHI; Toshihiro YOKOTA; Kuniaki SHIRAO; Hiroaki ONDA; Ikuo KOBA; Yasushi TSUJI; Haruhiko FUKUDA; Yasuyuki YAMASAKI; 丸山 哲生; Hiroyasu IGAKI; Masayoshi YOSHIMORI; Yanao OGURO; Masayuki ITABASH; Teruyuki HIROTA

doi:10.11280/gee1973b.36.23

Shinji NASU, Shigeaki YOSHIDA, Daizoh SAITOH, Hajime YAMAGUCHI, Toshihiro YOKOTA, Kuniaki SHIRAO, Hiroaki ONDA, Ikuo KOBA, Yasushi TSUJI, Haruhiko FUKUDA, Yasuyuki YAMASAKI, [in Japanese], Hiroyasu IGAKI, Masayoshi YOSHIMORI, Yanao OGURO, Masayuki ITABASH, Teruyuki HIROTA

Author information

Shinji NASU
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Shigeaki YOSHIDA
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Daizoh SAITOH
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Hajime YAMAGUCHI
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Toshihiro YOKOTA
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Kuniaki SHIRAO
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Hiroaki ONDA
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Ikuo KOBA
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Yasushi TSUJI
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Haruhiko FUKUDA
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Yasuyuki YAMASAKI
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
[in Japanese]
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Hiroyasu IGAKI
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Masayoshi YOSHIMORI
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Yanao OGURO
Department of Internal Medicine, National Cancer Center Hospital (NCCH)
Masayuki ITABASH
Division of Pathology, National Cancer Center Research Institute
Teruyuki HIROTA
Division of Pathology, National Cancer Center Research Institute

JOURNAL FREE ACCESS

1994 Volume 36 Issue 1 Pages 23-30_1

DOI https://doi.org/10.11280/gee1973b.36.23

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Abstract

During the period from 1962 and 1990, 27 lesions of 27 cases had been diagnosed histologically as upper gastrointestinal (Gl) carcinoid tumor at the NCCH. The endoscopic and pathological findings, and clinical aspects (diagnostic results, clinical course, etc., ) of these 27 cases were examined retrospectively and the following resutlts were obtained. lesions. Distant metastasis was detected in 5 of the 22 gastric lesions, and in 1 of the 5 lesions, liver metastasis was found 8 years after the curative resection. 2) Endoscopic gross appearance of the 27 lesions could be classified into the following 3 types; superficial, polypoid and advanced cancer-like types. Distant metastasis was seen in 5 gastric cases regardless of the endoscopic typing. In superficial type, it was very difficult to estimate the correct tumor size endoscopically, and in all of the cases affected area confirmed histologically was far broader than that estimated preoperatively, except for one case in which a minute duodenal lesion disappeared after biopsy. 3) In the 20 resected cases, the preoperative diagnosis of carcinoid tumor was extremely poor and it was correctly made in only 60% (12/20) of the cases. In conclusion, upper GI carcinoid tumor should be regarded as evidently malignat neoplasma, and followed up carefully after operation. Endoscopically, carcinoid tumor should be suspected not only from tumourous apperance but also from the superficial or hyperplastic changes.

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