1986 Volume 28 Issue 8 Pages 1902-1909_1
Two cases of early cancer of the papilla of Vater were reported. Case 1: 72-year-old man was admitted to our hospital with a complaint of epigastralgia. Slight elevation of the serum LAP, AL-P and γ-GPT was detected. Hypotonic duodenography and duodenofiberscopy showed a polypoid lesion of the papilla of Vater, and the biopsy specimens revealed adenoma, but the presence of focal malignancy could not be ruled out, Amputation of the papilla of Vater was performed. The histology of resected specimen revealed adenoma with focal carcinoma. The postoperative course of this patient has been uneventful. Case 2:53-year-old man was admitted to our hospital with complaints of upper abdominal pain and back pain. Routine examinations revealed the elevation of serum amylase and mild liver function impairment. From this results, acute pancreatitis was suspected. The conservative therapy for pancreatitis was effective. Hypotonic duodenography and duodenofiberscopy showed a polypoid lesion of the papilla of Vater, and the biopsy specimens revealed adenocarcinoma. Pancreoduodenectomy was performed, and resected specimen revealed adenoma with focal carcinoma. The post operative course has been uneventful. These two cases suggested the possibility of malignant transformation of adenoma of the papilla of Vater.
