Hypertension is frequently encountered during the emergence of general anethesia, caused by the stimulation of endotracheal tube, drug withdrawal, pain and so on.
In order to prevent this hypertension during the emergence period, nicardipine hydrochloride (0.01mg/kg to 0.02mg/kg) was administrated to twenty-two paients.
The effect of nicardipine was reduction of blood pressure and the rate pressure product was obtained within 5 minutes and significant.
These results indicate that the rapid and strong antihypertensive effect of nicardipine is useful and safe for the treatment during the emergence of general anethesia.